Welcome to SynapSpec

Latest version: v0.4.2 | Release Notes

SynapSpec is a comprehensive mass spectrum analysis tool designed for both beginners and advanced users. With intuitive GUI and powerful CLI interfaces, it provides everything you need for accurate spectrum processing and compound identification.

🚀 Quick Start

🖥️ GUI Interface

Launch the graphical interface for interactive analysis

Double-click the SynapSpec application icon

GUI Tutorial →

💻 CLI Interface

Run analysis with command-line for batch processing

synapspec run config.yaml
CLI Tutorial →

🔬 Core Features

Peptide Identification & Quantification

Advanced algorithms for accurate peptide identification with robust false discovery rate control and precise quantification across samples.

Deep Learning-based Spectral Library Generation

Advanced deep learning models for accurate spectral library prediction and generation, enabling enhanced peptide identification and DIA analysis.

Label-free Quantification

Support for both label-free and isobaric labeling method for multiplexed quantitative proteomics experiments.

DIA Analysis

Optimized workflows for data-independent acquisition and SWATH-MS analysis with spectral library generation and matching.

Statistical Analysis & Differential Expression

Integrated statistical tools for differential expression analysis and multiple testing correction.

📊 Supported Formats

Input Formats:

  • .raw
  • .d
  • .mzML

Library Formats:

  • .txt (MaxQuant format)
  • .tsv (MaxQuant format)

Output Formats:

  • .csv
  • .tsv
  • .parquet

🛠️ Installation

Get started with SynapSpec in minutes. Choose your platform: View detailed installation guide →

🌟 Need Help?

  • 📚 Documentation: Browse our comprehensive guides
  • 🐛 Bug Reports: GitHub Issues
  • 💬 Discussions: Community Forum
  • 📧 Support: contact@bionsight.com