Version 0.4.1

• CPU and GPU Versions
  • SynapSpec is now available in separate CPU and GPU versions, allowing users to choose the version that best suits their hardware configuration.
• Display and Naming
  • Updated application name from "synapspec" to "SynapSpec" throughout the interface(macOS).
• Data Export Quality
  • Improved precision formatting in quantification output files for better readability.
• Analysis Workflow
  • Enhanced stability when starting analysis tasks.
• Memory Management
  • Improved memory usage to prevent out-of-memory issues during large-scale analyses.
• Library Information Display
  • When a library is selected as input, you can now see detailed information including library size and number of candidates.

• Match Between Runs (MBR)
  • Resolved MBR workflow issues that prevented library generation.
  • Improved handling of intermediate files during processing.

Version 0.3.6

• Improved Worker Efficiency
  • Optimized worker utilization, resulting in faster task execution and overall improved processing speed.

• Python.NET Initialization
  • Fixed an issue where pythonnet was being unnecessarily loaded on worker types that do not require it.
• Application Shutdown
  • Fixed issue where application shutdown did not work properly.
• Linux GUI
  • Fixed process execution failure in Linux GUI environment.

Version 0.3.4

• Windows Analysis
  • Fixed error cases that occurred during analysis on Windows.

Version 0.3.3

• macOS Compatibility
  • Fixed issue where application could not open on macOS.

Version 0.3.2

• Configuration and Output
  • Renamed output columns and configuration parameters to be more intuitive and self-explanatory.

• Distribution Package
  • Fixed Linux executable permissions to be preserved in distribution package (users no longer need to manually set execute permissions).

Version 0.3.1

• Hardware Acceleration
  • Fixed issue where GPU acceleration was enabled

• Logging
  • Enhanced log messages to provide more meaningful information for debugging and monitoring.
  • Removed unnecessary log outputs to reduce noise and improve clarity.

Version 0.3.0

• Hardware Acceleration
  • Implements GPU acceleration for improved processing performance and faster analysis workflows.

• Enhanced Logging System
  • Improved log message formatting and information detail for better debugging and workflow monitoring.
  • Provides more comprehensive execution status tracking.
• Match-Between-Runs (MBR) Reporting
  • Adds detailed reporting functionality for Match-Between-Runs results.
  • Enables better tracking and validation of cross-run peptide identification transfer.

• GUI Icon Display
  • Fixed Flet GUI application icon rendering issue.

Version 0.2.16

• Workflow Execution
  • Fixed workflow execution error caused by missing package dependencies.

Version 0.2.15

• DIA Analysis Workflow
  • Implements an initial workflow for processing and quantifying Data-Independent Acquisition (DIA) mass spectrometry data.
• Semi-Specific Analysis Support
  • Supports 'semi-specific' search options, where peptides are required to follow the enzyme cleavage rule at only one terminus (N-terminus or C-terminus).
• Graphical User Interface (GUI)
  • Provides a GUI to configure and execute analysis pipelines as an alternative to the command-line interface.
• Automatic Configuration
  • Includes a preliminary feature to suggest analysis parameters based on input data.
• Versatile Data Import
  • Provides initial compatibility for reading native (raw) file formats from major mass spectrometry vendors, including:
    • .raw
    • .d directories
    • .mzML, .mzXML
• Cross-Platform Support
  • Designed for operation on Windows, macOS, and Linux operating systems.