precursors.csv

This file contains comprehensive precursor-level results with each row representing a single identified precursor ion.

Column Description

Column Description
elution_peak_width_rt Elution peak width based on retention time (seconds).
frame_scan_correlation Correlation between frame and scan dimensions.
rt_fwhm Full Width at Half Maximum (FWHM) of the RT peak.
mobility_fwhm FWHM of the mobility peak.
rt Observed retention time (seconds).
mobility Observed mobility value.
precursor_mz Observed precursor mass-to-charge ratio (m/z).
mobility_width Window width in the mobility (drift time) dimension.
precursor_index Internal index of the precursor (links to fragments).
is_decoy Whether the precursor is a decoy entry.
modified_sequence Peptide sequence including modifications.
precursor_charge Charge state of the precursor ion.
irt Indexed Retention Time (iRT) value.
n_aas Number of amino acids in the peptide.
n_mods Number of modifications in the peptide.
empirical_mz The library m/z value after calibration to experimental conditions.
isotope_ints Relative intensities of isotope peaks.
empirical_rt The library retention time after calibration to experimental conditions.
empirical_mobility The library mobility value after calibration to experimental conditions.
protein_accessions Protein accession IDs associated with the precursor.
delta_rt Difference between observed and predicted RT.
n_lys Number of lysine (K) residues.
n_arg Number of arginine (R) residues.
n_pro Number of proline (P) residues.
precursor_proba Probability score for precursor identification.
precursor_qvalue Precursor-level q-value (FDR-corrected).
filename Name of the file/run where the precursor was detected.
protein_group Representative accession of the protein group.
protein_groups All protein groups containing this precursor.
protein_qvalue Protein-level q-value (FDR-corrected).
ms2_raw_quantity Raw MS2 intensity.
ms2_quantity Normalized MS2 intensity.
protein_quantity Calculated protein-level quantification.

fragments.csv

This file contains fragment ion–level data associated with each precursor.
Each precursor may have multiple fragments corresponding to individual fragment ions.

Column Description

Column Description
precursor_index Index linking to the corresponding precursor in precursors.csv.
fragment_id Unique identifier of the fragment.
is_decoy Whether the fragment is a decoy.
filename File/run where the fragment was detected.
fragment_peak_area Fragment peak area (intensity).
fragment_mz Fragment mass-to-charge ratio (m/z).

Quantification Matrices (*.matrix.csv)

Quantification matrix at precursor or protein level.

Rows are IDs (precursor or protein).

Columns are filenames (runs) with measured values (usually normalized intensity).

File Format

  • Each row represents a unique precursor or protein.
  • Each column represents a filename (run).
  • Cell values contain the measured normalized intensity.

Columns

Column Description
<id> Unique precursor or protein identifier.
<filename> Normalized quantification value measured in that file/run.

Summary

  • precursors.csv: Main table linking identification, prediction, and quantification at the precursor level.
  • fragments.csv: Detailed fragment ion information, linked via precursor_index.
  • *.matrix.csv: Quantitative matrices summarizing normalized values across runs.

These files together provide complete traceability from fragment ions → precursors → proteins, enabling robust downstream analysis, visualization, and statistical inference.